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Use of addictive medication in the Czech Republic
Brožková, Lenka ; Gabrhelík, Roman (advisor) ; Rolová, Gabriela (referee)
Background: The use of psychoactive prescription drugs (PPDs) in the patient population is poorly studied in Czechia. Aims: (i) To investigate the prevalence of PPDs use; (ii) to estimate the extent of doctor shopping (DS); (iii) to explore the association between the repeated use of PPD, DS and subsequent addiction care. Design and setting: Pharmacoepidemiological study using the precription database and the database of reimbursed health services of health insurance company Zamestnanecka pojistovna Skoda (2012-2021). Participants: Insurees (n=146,177; male n=71,013; female n=75,164) represented by approximately 340,000 health records. Measurements: To identify drug use in the form of DS we analyzed prescription overlaps from multiple health care providers. The association between repeated use of PPD and provided health services was determined by analyzing the drug history of insurees who received any type of addiction service. Findings: We found that more than half of the insurees who used the opioid analgesic also used anxiolytic drugs in the same year. The highest proportion of insurees with DS was related to stimulant use (3.37%). Regarding opioid analgesics and benzodiazepines, the proportions were similar (OA 2.25%; BZD 2.37%). The number of duplicit prescriptions per doctor shopper was the...

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